Publicaciones (2016–2026)

Estabilidad del genoma y procesos mutacionales

  • Ruis C, Peacock TP, Polo LM, Masone D, … Floto RA. A lung-specific mutational signature enables inference of viral and bacterial respiratory niche. Microb Genom 10.1099/mgen.0.001018

 

 

 

  • Polo LM, Xu Y, Hornyak P, … Oliver AW, Pearl LH. Efficient single-strand break repair requires binding to both poly(ADP-ribose) and DNA by the central BRCT domain of XRCC1. Cell Rep 10.1016/j.celrep.2018.12.082

 

  • Alt A, Dang HQ, Wells OS, Polo LM, … Oliver AW. Specialized interfaces of Smc5/6 control hinge stability and DNA association. Nat Commun 10.1038/ncomms14011

 

  • Grundy GJ, Polo LM, Zeng Z, … Caldecott KW. PARP3 is a sensor of nicked nucleosomes and monoribosylates histone H2B(Glu2). Nat Commun 10.1038/ncomms12404

 

Trabajos en colaboración y desarrollos metodológicos

  • Zanetti FA, Fernandez I, … Celayes ME, Polo LM, … Delgui LR. On the role of VP3-PI3P interaction in birnavirus endosomal membrane targeting. eLife 10.7554/eLife.97261

 

  • Buzzatto MV, Benegas Guerrero FC, Álvarez PA, Zizzias MP, Polo LM, Tomes CN. Expression, purification and application of a recombinant, membrane permeating version of the light chain of botulinum toxin B. Biosci Rep 10.1042/BSR20240117

 

  • Di Bartolo AL, Caparotta M, Polo LM, Masone D. Myomerger induces membrane hemifusion and regulates fusion pore expansion. Biochemistry 10.1021/acs.biochem.3c00682

 

  • Rivero CV, Martínez SJ, … Polo LM, … Romano PS. Repurposing carvedilol as a novel inhibitor of the autophagy flux that affects parasite replication and survival. Front Cell Infect Microbiol 10.3389/fcimb.2021.657257